Data is sent and received over two wires (aka serial) to make interfacing rather easy. Temperature sensors can be interfaced to the vga ports to detect dangerous sutuations insde and outside servers or other valuable equipment. The SDA and SCL connections are the key points of interaction.
If we can connect sensor devices to the vga port, they we can go one step further and add microprocessors to control other devices. One such device that might be used is the ever popular Arduino. At the retail level, most Arduinos are sold on an interface board, but you can also use them as standalone chips. Now legacy personal computers are infinitely more valuable for the time being with the added power of the microprocessors.
There is enough information on the Arduino, that I should not have to elaborate here, The sky is the limit. What's your next project?